Folic Acid: A Potential Shield Against Lead and Autism?

October 24, 2024

Researchers at Simon Fraser University have made a groundbreaking discovery, suggesting that folic acid may reduce the risk of autistic-like behaviors in children exposed to lead during pregnancy.

Key Findings:

  1. Folic acid supplementation (0.4 mg/day) may mitigate lead’s neurotoxic effects.
  2. Low folic acid intake (<0.4 mg/day) strengthens the link between blood-lead levels and autistic-like behaviors.
  3. High folic acid supplementation (>1.0 mg/day) shows no additional benefits.

The Study:

Analyzing data from 2,000 Canadian women (MIREC study, 2008-2011), researchers measured blood-lead levels and folic acid supplementation during pregnancy. Children’s autistic-like behaviors were assessed using the Social Responsiveness Scale.

Implications:

  1. Folic acid’s neuroprotective effects align with Health Canada’s recommendations.
  2. Proper supplementation may lower autism risk associated with lead exposure.
  3. Study supports existing guidelines for folic acid intake during pregnancy.

Reference:

“Combined Exposure to Folate and Lead during Pregnancy and Autistic-Like Behaviors among Canadian Children” (Environmental Health Perspectives, October 16, 2024)

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