Unraveling the Origins of the Irish Potato Famine Pathogen

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4 weeks ago

A groundbreaking study led by researchers at North Carolina State University has shed new light on the origins of the devastating Irish potato famine pathogen, Phytophthora infestans. Through an exhaustive genetic analysis, the team has pinpointed the Andes Mountains in South America as the birthplace of this notorious pathogen.

A Century-Old Mystery Solved

Phytophthora infestans, the culprit behind the Irish potato famine, has been wreaking havoc on potato and tomato crops globally for centuries. Despite its notorious reputation, the pathogen’s origins remained a topic of debate among scientists. The new study puts this mystery to rest, providing conclusive evidence that the pathogen originated in the Andes Mountains before spreading to other parts of the world.

Genomic Evidence Reveals the Pathogen’s History

The research team compared the complete genomes of Phytophthora infestans with its close relatives, Phytophthora andina and Phytophthora betacei, both native to South America. The findings revealed striking genetic similarities among these species, solidifying the theory of the pathogen’s South American origin.

Implications for Climate Change and Crop Resistance

The study’s findings have significant implications for our understanding of the impact of climate change on crop resistance. As the Andean region faces increasing drought due to climate change, wild potato species that may hold the key to resistance against Phytophthora infestans are under threat.

A Call for Further Research

The researchers emphasize the need for further investigation into wild potato species from the Andes to uncover potential resistance to Phytophthora infestans. As the world grapples with the challenges of climate change and food security, understanding the origins and evolution of this devastating pathogen is more crucial than ever.

Reference:
“A pangenome analysis reveals the center of origin and evolutionary history of Phytophthora infestans and 1c clade species” (PLOS One, January 2025)

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