Yo-Yo Dieting Linked to Kidney Disease in Type 1 Diabetes Patients

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2 weeks ago

A recent study published in the Journal of Clinical Endocrinology & Metabolism reveals a shocking connection between yo-yo dieting and kidney disease in individuals with type 1 diabetes. The research suggests that unstable weight patterns can accelerate kidney function decline, emphasizing the importance of long-term weight stability.

The Hidden Dangers of Yo-Yo Dieting

Yo-yo dieting, or repeatedly losing and regaining weight, affects a significant portion of the population. This pattern has been linked to a higher risk of cardiovascular events and kidney disease in both the general population and individuals with type 2 diabetes.

Breakthrough Study Reveals Connection

The study, conducted by researchers from France, examined six years of body-weight indices for 1,432 participants with type 1 diabetes. The results showed that individuals with greater weight fluctuations experienced a 40% decline in kidney function, measured by estimated glomerular filtration rate (eGFR).

Why Yo-Yo Dieting Harms the Kidneys

While the exact mechanisms are still unclear, researchers hypothesize that insulin therapy, body-weight cycling, and added strain on the heart may contribute to kidney damage.

Reducing the Risks

To minimize the risks of yo-yo dieting and kidney disease, the study authors recommend focusing on long-term weight maintenance. Strategies aimed at promoting weight stability may have a positive impact on health outcomes.

Reference

“Body-Weight Cycling and Risk of Diabetic Kidney Disease in People with Type 1 Diabetes in the DCCT/EDIC Population” (4 February 2025, The Journal of Clinical Endocrinology & Metabolism)

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